The Santa Ana River is the largest river entirely within Southern California in the United States. It rises in the San Bernardino Mountains and flows for most of its length through San Bernardino and Riverside counties, before cutting through the northern San…The Santa Ana River is the largest river entirely within Southern California in the United States. It rises in the San Bernardino Mountains and flows for most of its length through San Bernardino and Riverside counties, before cutting through the northern Santa Ana Mountains via Santa Ana Canyon and flowing southwest through urban Orange County to drain into the Pacific Ocean. The Santa Ana River is 96 miles long, and its drainage basin is 2,650 square miles in size.
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