To refresh your memory, shortly before the events of Logan, Charles Xavier had a telepathic seizure which led to the deaths of multiple X-Men. This could be the event where Wolverine "let down the entire world", with Deadpool 3 taking place shortly after this incident but before Logan.

Marvel Studios recently released the much-anticipated trailer for Deadpool & Wolverine. The scene opens with Hugh Jackman in Logan’s trademark elongated sideburns sitting at a bar, with the bartender being less than welcoming.

As for who they're hunting down? The trailer includes a bald character played by Emma Corrin, who has long been rumored to play Cassandra Nova. The trailer as a whole is also packed with blink-and-you'll miss it nods and references that we can't wait to get our claws into.