The patient gives you a work accommodations form from her employer, which asks for a specific diagnosis supported by laboratory tests and imaging along with clinical information that meets certain ...

Among patients with resectable early-stage non–small-cell lung cancer (NSCLC), a perioperative approach that includes both neoadjuvant and adjuvant immune checkpoint inhibition may provide benefit ...

The effect of early as compared with later initiation of direct oral anticoagulants (DOACs) in persons with atrial fibrillation who have had an acute ischemic stroke is unclear. We performed an ...

Disabling pansclerotic morphea (DPM) is a rare systemic inflammatory disorder, characterized by poor wound healing, fibrosis, cytopenias, hypogammaglobulinemia, and squamous-cell carcinoma. The cause ...

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Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services.

In the United States, a chronic shortage of platelets for transfusion is jeopardizing patient outcomes. The two technologies ...

Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services.

We conducted an open-label, randomized, noninferiority trial involving patients referred to ECT clinics for treatment-resistant major depression. Patients with treatment-resistant major depression ...

Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services.

Initial diagnostic ultrasonography for suspected pediatric distal forearm fractures is accurate and timely. Whether this approach is noninferior to radiography for later physical function is unclear.