2025 — Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the ...

These achievements lay an important foundation for clinical trials targeting the genetic cause of the disease. Huntington's disease is a genetic condition caused by an unusually long DNA sequence ...

The disease and cause is personal for Noreen Hoft, vice president of the chapter’s Board of Directors. “My husband is a person who has Huntington’s disease,” Hoft said. “It being genetic ...

Huntington’s disease was long thought to be caused by the slow buildup of a toxic protein, but new research has revealed that it’s actually driven by the expansion of a gene that, at a certain ...

The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have ... of people with Alzheimer’s disease, and has long been viewed by researchers and pharmaceutical ...

Usually a protein is capable of finding its functional or native ... such is the case in Huntington's disease. Remarkably, the toxic configuration is often able to interact with other native ...

Roche has stopped dosing in a phase 3 trial of tominersen, a potential Huntington’s disease (HD ... first drug to treat the underlying cause of the disease, which leads to devastating ...

A drug originally developed for high blood pressure could find a new use in the treatment of Huntington's disease, thanks to an artificial intelligence-based drug discovery programme at Spain's ...

Huntington's disease ... Center of Excellence by the Huntington's Disease Society of America; it is also a member of the Huntington Study Group, a consortium of academic clinicians and researchers ...