Berks County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the county's population was 428,849. The county seat is Reading, the fourth-most populous city in the state. The county is part of the South Central Pennsylvania region …Berks County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the county's population was 428,849. The county seat is Reading, the fourth-most populous city in the state. The county is part of the South Central Pennsylvania region of the state.
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