The cause of lupus has long escaped doctors trying to treat the autoimmune disease. However, a study published this week ...

Researchers at Northwestern Medicine and Brigham and Women’s Hospital say they’ve discovered a root cause of lupus, a disease that affects hundreds of thousands of people in the U.S ...

The nonprofit Lupus Foundation of America estimates closer to 1.5 million people are affected. The study identified a cause ...

July 10, 2024 – Researchers have identified a possible cause of lupus that could lead to a cure for the life-threatening condition, potentially stopping the immune system from mistakenly waging ...

The work may also help explain why lupus is about 10 times more frequent in females than in males. As TLR7 sits on the X chromosome, females have two copies of the gene while males have one ...

When the mutation was modeled in mice using CRISPR gene editing, the mice showed symptoms of lupus, suggesting that dysfunction in TLR7 can indeed cause the disease. Although every lupus patient may ...