For the second time in as many days, Democratic leaders on Friday failed to pass a deal on a nearly $3 billion spending bill in the Massachusetts House, continuing a standoff with the small GOP caucus.

A compromise budget deal between the Massachusetts House and Senate sets aside $250 million to prop up the state’s under-resourced shelter system, with a portion of the funds going toward opening an overflow site to house homeless families by the end of December.

Democrats in the Massachusetts House and Senate say they have reached a deal on a supplemental budget that will provide additional funding for the state’s overtaxed shelter system, but Republicans took a rare step to put up a roadblock.