Israel launched large-scale airstrikes against Iran, saying it had “no choice” but to destroy Tehran’s nuclear program — with Iran quickly responding Friday by launching 100 drones and calling it a “declaration of war.

Israel attacked Iran early yesterday with a barrage of airstrikes that took out top military officers, and hit nuclear and missile sites, calling it just the beginning and raising the potential for an all-out war between the two Middle East adversaries. It appeared to be the most significant attack Iran has faced since its 1980s war with Iraq.